Topiramate Induced Acute Angle Closure and Myopia with Ciliochoroidal Effusion

Abstract

Topiramate, a sulfamate substituted monosaccharide, is a widely used antiepileptic drug which has now gained widespread use for migraine prophylaxis and various other conditions. This drug has been associated with ocular side effects, of which secondary acute angle closure is a rare idiosyncratic reaction which can result in blindness if not identified and treated promptly. This case report demonstrates a middle-aged woman who presented with bilateral acute angle closure and myopia with suprachoroidal effusion. This serious ocular side effect was reversed by timely intervention. Hence it is important that the treating physician is aware of this rare condition and warn the patients while prescribing the drug.