Prevalence of Vitamin D Deficiency in Patients with Inflammatory Bowel Disease

Abstract

Background: Vitamin D deficiency in inflammatory bowel disease (IBD) patients may have important clinical implications. Therefore, it is important to investigate the prevalence of vitamin D deficiency in patients with IBD to better understand its impact on disease management and outcomes.
Objectives: To assess the prevalence of vitamin D deficiency in patients with IBD using a radioimmunoassay method.
Material & Methods: This was a prospective, observational study conducted at the Department of Medicine, Government of Medical College Jammu, India for a year from 1 November 2021 to 31 October 2022. Adult patients from OPD and IPD with biopsy proven IBD were included.
Results: A total of 40 patients were included in the study with mean age of 38.7 years. Majority of patients (70%) were male and 50% patients belonged to age group of 30-60 years. The mean vitamin D level was 25.6 ng/mL and 62.5% of patients observed with vitamin D deficiency. Both genders and age were affected, with a significant proportion of patients having abnormal vitamin D levels. The vitamin D level was found to be comparable between both genders (P>0.05) and age groups (0.229).
Conclusion: The present study investigated the high prevalence of vitamin D deficiency among patients with IBD. Additionally, patients were supplemented with vitamin D and were followed for further monitoring and evaluation for their outcomes.