Histopathological Study of Bone Tumours- 4 Years Study in A Tertiary Care Centre

Abstract

Background: Tumors of the bone constitute 0.5% of the total world cancer incidence. Histogenesis of these tumors is still uncertain. Relevant demographic features such as age, sex and skeletal site; detailed clinical history and radiographic findings are important for a conclusive diagnosis.
Objective: To evaluate the histopathological features of bone tumours and to correlate these bone lesions with age, sex, clinical presentation, anatomical location and radiological findings.
Material & Method: This retrospective study was conducted in the Postgraduate Department of Pathology, GMCH Jammu for a period of 4 years. The present study included 64 cases of bone tumours admitted to GMCH Jammu. Ethical clearance has been taken from the ethical committee of the institute GMCH Jammu.
Result: A total of 64 cases were studied out of which 36 (56.26%) cases were benign; 17 (26.56%) cases were of primary malignant lesion and 11 (17.18%) cases were of metastasis to bone. Among benign tumours, most common tumour was Giant Cell Tumor (GCT) and among malignant tumours most common tumour was osteosarcoma.
Conclusion: Bone tumours pose a challenge to the Pathologists, Radiologists and Orthopaedic surgeon because of their varied presentation, uncertain histogenesis and their behaviour to treatment.