Schwannoma with Focal Malignant Transformation (MPNST) - A Rare Case Report

Authors

  • Vaishnavi Selvaraju
  • Yamini PM
  • Jaya Ganesh

Keywords:

MPNST, Schwannoma, Histopathology, Differential diagnosis

Abstract

MPNST is a malignant neoplasm commonly arising from a pre-existing nerve sheath tumor in neurofibromatosis type 1 (NF1) or in the setting of prior radiation therapy with an incidence of 0.001% in general population. This case is about a 55-year-old male who was diagnosed with schwannoma in left para-vertebral region extending into posterior mediastinum radiologically, showed a focal malignant transformation histopathologically. Malignant peripheral nerve sheath tumor (MPNST) arising from a schwannoma is an extremely rare entity, so it’s essential for pathologists and surgeons to be aware of the possibility to make accurate diagnosis and choose best treatment options.

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Published

10-01-2024

How to Cite

1.
Selvaraju V, Yamini PM, Jaya Ganesh. Schwannoma with Focal Malignant Transformation (MPNST) - A Rare Case Report. JK Science [Internet]. 2024 Jan. 10 [cited 2024 Nov. 24];26(1):62-4. Available from: https://journal.jkscience.org/index.php/JK-Science/article/view/248

Issue

Section

CASE REPORTS