Retrospective Observational Study of Hematological and Biochemical Parameters of COVID 19 Patients

Abstract

Background: COVID 19 has a potential to spread exponentially during its incubation period. Early diagnosis and management are therefore key in checking its progression.
Aims and Objectives: The aim of the present study is to make a retrospective assessment of hematological and biochemical parameters, along with inflammatory biomarkers, in COVID 19 patients to ascertain if they act as independent factors in disease prognosis.
Study Design: A retrospective observational study was conducted on 120 patients, in the Department of Biochemistry in collaboration with Department of Pathology, Government Medical College, Jammu.
Material and Methods: All patients admitted with positive real time reverse transcriptase polymerase chain reaction (RT-PCR) and hospitalized in various COVID 19 wards of GMC Jammu and Patients in the age group of 18 years and above were included for the current analysis.
Results: There were, 79 (65.83%) males and 41 (34.17%) females. 75.83% patients recovered without any adverse outcome, 9.17% patients were severely/critically ill, 2.5% died. Significantly higher neutrophils (71.34 ± 11.55) were associated with prolonged hospital stay. 46/120 (38.33%) patients had co-morbidities, 13 (10.83%) patients had Diabetes Mellitus and 11 (9.17%) were hyper-tensive. D-dimer, CRP and Ferritin levels were significantly elevated, NLR was seen significantly higher among patients (3.99 ± 1.87) with prolonged stay and severity of disease.
Conclusions: Hematological parameters and inflammatory biomarkers in COVID 19 patients can potentially act as independent factors and affect the disease prognosis and treatment process